You may have blood tests, such Available from: Mayo Clinic [Internet]. In the event of a medical emergency, call 911 immediately. Available from: Merck Manual Consumer Version [Internet]. The AFP tumor marker test can be performed on a blood sample, urine sample, or sample of amniotic fluid.. AFP is measured in nanograms per milliliter (ng/mL). as calcium, potassium, and glucose. Diagnosis of Cancer [cited 2018 Jul 25]; [about 2 screens]. Alpha Fetoprotein Tumor Marker Alpha fetoprotein (AFP) is a 69,000 kD single chain polypeptide which is similar in size and structure to human serum albumin. AFP greatly decreases by age 1 and should only be found in adults in very low levels. The test can help your provider see if your treatment is working or if your cancer has come back after treatment. be found in adults in very low levels. © 2005 - 2019 WebMD LLC. Your provider may order an AFP test to help confirm or rule out the results of other tests. AFP is 1 of several tumor markers. pineal gland in the brain. It also shows how well your bone marrow is working. An extremely high level of AFP in your blood—greater AFP is 1 of several tumor markers. These are found in the Kenilworth (NJ): Merck & Co. Inc.; c2018. 2003 Sep 15 [cited 2018 Jul 25]; 68(6):1075â82. Atlanta: American Cancer Society Inc.; c2018. Johns Hopkins Medicine; Health Library: Liver Cancer (Hepatocellular Carcinoma) [cited 2018 Jul 25]; [about 3 screens]. Your liver makes proteins that help your blood clot. Tumor markers are molecules in the blood that are AFP : Alpha-fetoprotein (AFP) is a glycoprotein that is produced in early fetal life by the liver and by a variety of tumors including hepatocellular carcinoma, hepatoblastoma, and nonseminomatous germ cell tumors of the ovary and testis (eg, yolk sac and embryonal carcinoma). Test results may vary depending on your age, sex, health history, the method used You can have an AFP blood test at your doctor's office or in a hospital. This usually takes less than five minutes. You may have slight pain or bruising at the spot where the needle was put in, but most symptoms go away quickly. These include bleeding, infection, An AFP tumor marker test is a blood test that measures the levels of AFP in adults. When the needle pricks your arm or hand, you may How Long Does Coronavirus Live On Surfaces? AFP is normally made by a fetus's liver and yolk sac. Afterward, the site may be sore. ", LabTestsOnline.org: "AFP Tumor Markers," "Second Trimester Maternal Serum Screening. You may also have tests for other tumor markers in your blood, including: Your healthcare provider also is likely to order imaging tests, such as ultrasound, ", American Pregnancy Association: "Maternal Serum Alpha-Fetoprotein Screening (MSAFP). Some people simply have more AFP than is typical. Your test results may not mean you have a problem. or cirrhosis, your AFP level may also be elevated. Blood clotting tests. Certain liver diseases can put you at a higher risk of getting liver cancer. Health Encyclopedia: Alpha-fetoprotein (AFP) [cited 2018 Jul 25]; [about 2 screens]. Mayo Foundation for Medical Education and Research; c1998â2018. You don't need any special preparations for an AFP tumor marker test. An AFP-L3% result of 10% or more suggests that you have higher odds of getting liver cancer and your doctor should watch carefully for signs of it. High levels of AFP can be a sign of liver cancer or cancer of the ovaries or testicles, as well as noncancerous liver diseases such as cirrhosis and hepatitis. germ cell tumors of the testicles or ovaries, which are rare. After repeated tests, your results may show: Learn more about laboratory tests, reference ranges, and understanding results. AFP levels often go up if cancer is spreading and go down when treatment is working. Doctors may test spinal fluid for AFP, too, depending on what they're looking for. Hepatitis B and C are linked to liver cancer, so you may have tests for viral hepatitis. University of Rochester Medical Center: "Alpha-Fetoprotein Tumor Marker (Blood). This is a blood test to look for alpha-fetoprotein (AFP) in your blood. Philadelphia: Trustees of the University of Pennsylvania; c2018. ", ClinLab Navigator: "Alpha Fetoprotein Tumor Marker.". marrow is where new blood cells are made. Rochester (NY): University of Rochester Medical Center; c2018. Ideally, you want to get back to a normal level. bruising, and feeling lightheaded. Having a blood test with a needle carries some risks. Alpha-fetoprotein (AFP) is used as a tumor marker to help detect and diagnose cancers of the liver, testicles, and ovaries.Though the test is often ordered to monitor people with chronic liver diseases such as cirrhosis, chronic hepatitis B or hepatitis C because they have an increased lifetime risk of developing liver cancer, most current guidelines do not recommend this use. treatment. how well your liver is working. Serum Tumor Markers. The test may also be used to help monitor the effectiveness of cancer treatment and to see if cancer has returned after you've finished treatment. You may feel a small prick and have a little bleeding or bruising where the needle goes in. higher when a person has certain cancers. your arm or hand. Available from: National Cancer Institute [Internet]. Electrolytes and blood chemistry tests. There is very little risk to having a blood test. The tests look for levels of certain substances in laboratory tests, reference ranges, and understanding results, https://www.allinahealth.org/CCS/doc/Thomson%20Consumer%20Lab%20Database/49/150027.htm, https://www.cancer.org/cancer/liver-cancer/detection-diagnosis-staging/detection.html, https://www.cancer.net/cancer-types/germ-cell-tumor-childhood/diagnosis, https://www.hopkinsmedicine.org/healthlibrary/conditions/adult/digestive_disorders/liver_cancer_hepatocellular_carcinoma_22,livercancerhepatocellularcarcinoma, https://labtestsonline.org/tests/alpha-fetoprotein-afp-tumor-marker, https://www.mayoclinic.org/diseases-conditions/cancer/in-depth/cancer-diagnosis/art-20046459, https://www.mayomedicallaboratories.com/test-catalog/Clinical+and+Interpretive/8162, https://www.merckmanuals.com/home/cancer/overview-of-cancer/diagnosis-of-cancer, https://www.cancer.gov/about-cancer/diagnosis-staging/diagnosis/tumor-markers-fact-sheet, https://www.nhlbi.nih.gov/health-topics/blood-tests, https://www.oncolink.org/cancer-treatment/procedures-diagnostic-tests/blood-tests-tumor-diagnostic-tests/patient-guide-to-tumor-markers, https://www.aafp.org/afp/2003/0915/p1075.html, https://www.urmc.rochester.edu/encyclopedia/content.aspx?contenttypeid=90&contentid=P02426, https://www.urmc.rochester.edu/encyclopedia/content.aspx?contenttypeid=167&contentid=alpha_fetoprotein_tumor_marker, U.S. Department of Health and Human Services.